Rare Cholestatic Form of Stauffer Syndrome
Sharon XH Hu and Adel Ekladious
A 57-year-old man with inexplicable fevers and deranged liver function tests was found to have new
renal cell carcinoma on imaging without metastasis. Following surgical resection of the tumour, his
fevers immediately disappeared. Stauffer syndrome describes fever associated with renal cell carcinoma
and may have accompanying deranged liver biochemistry. Antibiotics should not be automatically
prescribed in clinically stable patients who have negative septic and hepatic screens. Instead, a wide
differential net should be cast, including for renal cell carcinoma as a potential diagnosis.
