TY - JOUR AU - Dr. Mungara Kiran Kumar AU - T Sri Venkata Narayana AU - T Yaswi Satya Akshith AU - R Srivatsan PY - 2026 DA - 2026/03/15 TI - A Deep Learning Framework for Accurate Skin Disease Diagnosis Using CNNs JO - Global Journal of Engineering Innovations and Interdisciplinary Research VL - 6 IS - 3 AB - The proposed project is an automated skin disease diagnosis framework based on deep learning consisting of convolutional neural networks implemented in a web-based application. The system will have two different diagnostic functions, which include the classification of the skin disease and identifying the type of skin cancer. The framework applies the transfer learning based on the pretrained convolutional neural network models, with a ResNet50-based model applied to general skin disease and DenseNet201-based model applied to skin cancer. Both models accept the dermal images resized to 224 x 224 pixels and then they do multiclass classification with the help of the softmax activation. The training plan involves extraction of features and refinement of the deeper layers to promote the domainspecific learning of features. Regularization methods like dropout and batch normalization are also added in order to enhance generalization and minimize overfitting. The trained models are deployed in a system that is built on Flask, which allows authentication of the users, uploading of images and real time inference. The prediction consists of class label predictions and confidence scores and class probability distributions. The dual-model architecture enables the system to respond to the different degrees of diagnostic complexity and at the same time be computationally efficient. The framework offers an organized system of applying deep learning models to practical healthcare assistance systems that will allow the opportunity to conduct the initial screening of skin conditions in an accessible and automatic manner. SN - 3066-1226 UR - https://dx.doi.org/10.33425/3066-1226.1274 DO - 10.33425/3066-1226.1274